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Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix

The neural extracellular matrix (ECM) is enriched with hyaluronic acid, chondroitin sulfate proteoglycans (CSPGs) and the glycoprotein tenascin-R, which play important roles in synaptic plasticity, as shown by studies of the CA1 region of the hippocampus. However, ECM molecules are strongly expresse...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Hayani, Hussam, Song, Inseon, Dityatev, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988902/
https://ncbi.nlm.nih.gov/pubmed/29899690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00149
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