Berberine Attenuates Macrophages Infiltration in Intracranial Aneurysms Potentially Through FAK/Grp78/UPR Axis

Background: Inflammatory cells, such as macrophages, play key roles in the pathogenesis of intracranial aneurysms (IAs). Berberine (BBR), an active component of a Chinese herb Coptis chinensis French, has been shown to have anti-inflammatory properties through suppressing macrophage migration in var...

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Vydáno v:Front Pharmacol
Hlavní autoři: Quan, Kai, Li, Sichen, Wang, Dongdong, Shi, Yuan, Yang, Zixiao, Song, Jianping, Tian, Yanlong, Liu, Yingjun, Fan, Zhiyuan, Zhu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988844/
https://ncbi.nlm.nih.gov/pubmed/29899701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00565
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