Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera

A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, we utilized probes comprising headless, HA stabilized stem (SS) to determine t...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yassine, Hadi M., McTamney, Patrick M., Boyington, Jeffery C., Ruckwardt, Tracy J., Crank, Michelle C., Smatti, Maria K., Ledgerwood, Julie E., Graham, Barney S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988737/
https://ncbi.nlm.nih.gov/pubmed/29872070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26538-7
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