Early transcriptomic changes in the ileal pouch provide insight into the molecular pathogenesis of pouchitis and ulcerative colitis

BACKGROUND: Ulcerative colitis (UC) only involves the colonic mucosa. Yet, nearly 50% of UC patients who undergo total proctocolectomy with ileal pouch anal anastomosis (IPAA) develop UC-like inflammation of the ileal pouch (pouchitis). In contrast, patients with familial adenomatous polyposis (FAP)...

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Dades bibliogràfiques
Publicat a:Inflamm Bowel Dis
Autors principals: Huang, Yong, Dalal, Sushila, Antonopoulos, Dionysios, Raffals, Laura H., Dolan, Kyle, Weber, Christopher, Messer, Jeannette, Jabri, Bana, Bendelac, Albert, Eren, A. Murat, Rubin, David T., Sogin, Mitch, Chang, Eugene B.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988644/
https://ncbi.nlm.nih.gov/pubmed/28221248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001027
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