Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas

High-grade gliomas (HGG), including glioblastomas, are characterized by invasive growth, resistance to therapy, and high inter- and intra-tumoral heterogeneity. The key histological hallmarks of glioblastoma are pseudopalisading necrosis and microvascular proliferation, which allow pathologists to d...

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Bibliographic Details
Published in:Glia
Main Authors: Herting, C. J., Chen, Z., Pitter, K. L., Szulzewsky, F., Kaffes, I., Kaluzova, M., Park, J. C., Cimino, P. J., Brennan, C., Wang, B., Hambardzumyan, D.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988206/
https://ncbi.nlm.nih.gov/pubmed/28836293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23203
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