लोड हो रहा है...
A Transcriptional Regulatory Network Containing Nuclear Receptors and Long Noncoding RNAs Controls Basal and Drug-Induced Expression of Cytochrome P450s in HepaRG Cells
Cytochrome P450 (P450) enzymes are responsible for metabolizing drugs. Expression of P450s can directly affect drug metabolism, resulting in various outcomes in therapeutic efficacy and adverse effects. Several nuclear receptors are transcription factors that can regulate expression of P450s at both...
में बचाया:
| में प्रकाशित: | Mol Pharmacol |
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| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5988030/ https://ncbi.nlm.nih.gov/pubmed/29691280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.112235 |
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