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Long-term safety of tiotropium/olodaterol Respimat(®) in patients with moderate-to-very severe COPD and renal impairment in the TONADO(®) studies

INTRODUCTION: The safety, lung function efficacy, and symptomatic benefits of combined tiotropium and olodaterol in patients with COPD were established in the 1-year TONADO(®) studies (NCT01431274; NCT01431287). As tiotropium is predominantly excreted by the kidneys, the long-term safety profile of...

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Dettagli Bibliografici
Pubblicato in:Int J Chron Obstruct Pulmon Dis
Autori principali: LaForce, Craig, Derom, Eric, Bothner, Ulrich, Kloer, Isabel M, Trampisch, Matthias, Buhl, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987861/
https://ncbi.nlm.nih.gov/pubmed/29910611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S161489
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