Effects of the combination of As(2)O(3) and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1

CONTEXT: Previous studies have demonstrated that 3′-azido-3′-deoxythymidine (AZT) and arsenic trioxide (As(2)O(3)), traditional chemotherapy agents, can synergically inhibit the growth of hepatocellular carcinoma cells. However, the molecular mechanisms underlying As(2)O(3) and AZT anti-hepatoma act...

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Publicat a:Onco Targets Ther
Autors principals: Zhao, Chuan, Wang, Mei, Liu, Yu, Liang, Yongjuan, Han, Li, Chen, Che
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987793/
https://ncbi.nlm.nih.gov/pubmed/29910624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S155169
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