DOWNREGULATION OF THE ANGIOTENSIN-CONVERTING ENZYME 2/ANGIOTENSIN-(1-7)/MAS RECEPTOR AXIS IN HEART AND KIDNEY OF TRANSGENIC MICE OVEREXPRESSING GROWTH HORMONE

Altered function of the renin-angiotensin system (RAS) could be a contributing factor to the cardiac and renal alterations induced by growth hormone (GH) excess. Increased angiotensin (Ang) II levels, arising from the action of Ang converting enzyme (ACE) exerts deletereous effects mediated mainly b...

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Vydáno v:J Endocrinol
Hlavní autoři: Muñoz, Marina C., Burghi, Valeria, Miquet, Johanna G., Giani, Jorge F., Banegas, Ricardo D., Toblli, Jorge E., Kopchick, John J., Bartke, Andrzej, Dominici, Fernando P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987768/
https://ncbi.nlm.nih.gov/pubmed/24756097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-13-0497
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