DOWNREGULATION OF THE ANGIOTENSIN-CONVERTING ENZYME 2/ANGIOTENSIN-(1-7)/MAS RECEPTOR AXIS IN HEART AND KIDNEY OF TRANSGENIC MICE OVEREXPRESSING GROWTH HORMONE

Altered function of the renin-angiotensin system (RAS) could be a contributing factor to the cardiac and renal alterations induced by growth hormone (GH) excess. Increased angiotensin (Ang) II levels, arising from the action of Ang converting enzyme (ACE) exerts deletereous effects mediated mainly b...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Muñoz, Marina C., Burghi, Valeria, Miquet, Johanna G., Giani, Jorge F., Banegas, Ricardo D., Toblli, Jorge E., Kopchick, John J., Bartke, Andrzej, Dominici, Fernando P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987768/
https://ncbi.nlm.nih.gov/pubmed/24756097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-13-0497
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