Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1

BACKGROUND: Obesity was a recognized risk factor for the development and progression of hepatocellular carcinoma (HCC). However, the effects and mechanisms by which obesity promotes HCC metastasis remain poorly understood. MATERIALS AND METHODS: We cultured adipocyte induced by preadipocyte 3T3-L1 i...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Chen, Yang, Zhang, Fan, Zhao, Yawei, He, Kan, Zheng, Xiao, Pan, Yue, Shao, Dan, Shang, Pei, Yang, Yongsheng, Zhang, Dan, Xie, Yingjun, Yao, Xiaoxiao, Chen, Li, Li, Jing, Zhang, Xuewen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987752/
https://ncbi.nlm.nih.gov/pubmed/29910623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S162978
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