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Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics
Single-headed myosin 1 has been identified in neurons, but its function in these cells is still unclear. We demonstrate that depletion of myosin 1b (Myo1b), inhibition of its motor activity, or its binding to phosphoinositides impairs the formation of the axon, whereas overexpression of Myo1b increa...
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| Опубликовано в: : | J Cell Biol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Rockefeller University Press
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5987710/ https://ncbi.nlm.nih.gov/pubmed/29588377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703205 |
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