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Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke

BACKGROUND: Subtle adjustment of the activation status of CNS resident microglia and peripheral macrophages, to promote their neuroprotective and neuroregenerative functions, may facilitate research towards curing neurodegenerative disorders. In the present study, we investigated whether targeted in...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Hamzei Taj, Somayyeh, Le Blon, Debbie, Hoornaert, Chloé, Daans, Jasmijn, Quarta, Alessandra, Praet, Jelle, Van der Linden, Annemie, Ponsaerts, Peter, Hoehn, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987479/
https://ncbi.nlm.nih.gov/pubmed/29866203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1212-7
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