Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults

BACKGROUND: Mass cytometry, or CyTOF (Cytometry by Time-of-Flight), permits the simultaneous detection of over 40 phenotypic and functional immune markers in individual cells without the issues of spectral overlap seen in traditional flow cytometry. METHODS: In this study, we applied CyTOF to compre...

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Gepubliceerd in:J Transl Med
Hoofdauteurs: Lingblom, Christine M. D., Kowli, Sangeeta, Swaminathan, Nithya, Maecker, Holden T., Lambert, Stacie L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987461/
https://ncbi.nlm.nih.gov/pubmed/29866115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1528-1
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