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Predicting the in vivo pulmonary toxicity induced by acute exposure to poorly soluble nanomaterials by using advanced in vitro methods

BACKGROUND: Animal models remain at that time a reference tool to predict potential pulmonary adverse effects of nanomaterials in humans. However, in a context of reduction of the number of animals used in experimentation, there is a need for reliable alternatives. In vitro models using lung cells r...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Loret, Thomas, Rogerieux, Françoise, Trouiller, Bénédicte, Braun, Anne, Egles, Christophe, Lacroix, Ghislaine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987386/
https://ncbi.nlm.nih.gov/pubmed/29866184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-018-0260-6
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