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Filopodia Conduct Target Selection in Cortical Neurons using Differences in Signal Kinetics of a Single Kinase

Dendritic filopodia select synaptic partner axons by interviewing the cell surface of potential targets, but how filopodia decipher the complex pattern of adhesive and repulsive molecular cues to find appropriate contacts is unknown. Here we demonstrate in cortical neurons that a single cue is suffi...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Mao, Yu-Ting, Zhu, Julia X., Hanamura, Kenji, Iurilli, Giuliano, Datta, Sandeep R., Dalva, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987257/
https://ncbi.nlm.nih.gov/pubmed/29731254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.04.011
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