AGING ATTENUATES REDOX ADAPTIVE HOMEOSTASIS AND PROTEOSTASIS IN FEMALE MICE EXPOSED TO TRAFFIC-DERIVED NANOPARTICLES (‘VEHICULAR SMOG’)

Environmental toxicants are catalysts for protein damage, aggregation, and the aging process. Fortunately, evolution selected adaptive homeostasis as a system to mitigate such damage by expanding the normal capacity to cope with toxic stresses. Little is known about the subcellular degradative respo...

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Publicado no:Free Radic Biol Med
Main Authors: Pomatto, Laura C.D., Cline, Mayme, Woodward, Nicholas, Pakbin, Payam, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Forman, Henry Jay, Davies, Kelvin J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987225/
https://ncbi.nlm.nih.gov/pubmed/29709705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.04.574
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