Mitochondrial Proteome Disruption in the Diabetic Heart Through Targeted Epigenetic Regulation at the Mitochondrial Heat Shock Protein 70 (mtHsp70) Nuclear Locus

Greater than 99% of the mitochondrial proteome is nuclear-encoded. The mitochondrion relies on a coordinated multi-complex process for nuclear genome-encoded mitochondrial protein import. Mitochondrial heat shock protein 70 (mtHsp70) is a key component of this process and a central constituent of th...

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Bibliografiske detaljer
Udgivet i:J Mol Cell Cardiol
Main Authors: Shepherd, Danielle L., Hathaway, Quincy A., Nichols, Cody E., Durr, Andrya J., Pinti, Mark V., Hughes, Kristen M., Kunovac, Amina, Stine, Seth M., Hollander, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987221/
https://ncbi.nlm.nih.gov/pubmed/29733819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.04.016
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