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Quantum Chemical Approaches in Structure-Based Virtual Screening and Lead Optimization

Today computational chemistry is a consolidated tool in drug lead discovery endeavors. Due to methodological developments and to the enormous advance in computer hardware, methods based on quantum mechanics (QM) have gained great attention in the last 10 years, and calculations on biomacromolecules...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Cavasotto, Claudio N., Adler, Natalia S., Aucar, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986912/
https://ncbi.nlm.nih.gov/pubmed/29896472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00188
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