Relapsing–Remitting Multiple Sclerosis Is Characterized by a T Follicular Cell Pro-Inflammatory Shift, Reverted by Dimethyl Fumarate Treatment

Multiple sclerosis (MS) is considered a T cell-mediated autoimmune disease, although several evidences also demonstrate a B cell involvement in its etiology. Follicular T helper (Tfh) cells, a CXCR5-expressing CD4+ T cell subpopulation, are essential in the regulation of B cell differentiation and m...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Cunill, Vanesa, Massot, Margarita, Clemente, Antonio, Calles, Carmen, Andreu, Valero, Núñez, Vanessa, López-Gómez, Antonio, Díaz, Rosa María, Jiménez, María de los Reyes, Pons, Jaime, Vives-Bauzà, Cristòfol, Ferrer, Joana Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986897/
https://ncbi.nlm.nih.gov/pubmed/29896193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01097
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