Estrogen Promotes Mandibular Condylar Fibrocartilage Chondrogenesis and Inhibits Degeneration via Estrogen Receptor Alpha in Female Mice

Temporomandibular joint degenerative disease (TMJ-DD) is a chronic form of TMJ disorder that specifically afflicts people over the age of 40 and targets women at a higher rate than men. Prevalence of TMJ-DD in this population suggests that estrogen loss plays a role in the disease pathogenesis. Thus...

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Udgivet i:Sci Rep
Main Authors: Robinson, Jennifer L., Soria, Paola, Xu, Manshan, Vrana, Mark, Luchetti, Jeffrey, Lu, Helen H., Chen, Jing, Wadhwa, Sunil
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986784/
https://ncbi.nlm.nih.gov/pubmed/29867155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26937-w
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