Population Pharmacokinetic Analysis of Asunaprevir in Subjects with Hepatitis C Virus Infection

INTRODUCTION: Asunaprevir (ASV) is a potent, pangenotypic, twice-daily hepatitis C virus (HCV) NS3 inhibitor indicated for the treatment of chronic HCV infection. METHODS: A population pharmacokinetic (PPK) model was developed using pooled ASV concentration data from 1239 HCV-infected subjects who r...

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Bibliographic Details
Published in:Infect Dis Ther
Main Authors: Zhu, Li, Li, Hanbin, Chan, Phyllis, Eley, Timothy, Gandhi, Yash, Bifano, Marc, Osawa, Mayu, Ueno, Takayo, Hughes, Eric, AbuTarif, Malaz, Bertz, Richard, Garimella, Tushar
Format: Artigo
Language:Inglês
Published: Springer Healthcare 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986681/
https://ncbi.nlm.nih.gov/pubmed/29589331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40121-018-0197-y
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