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Elucidation of the critical epitope of an anti-EGFR monoclonal antibody EMab-134

The epidermal growth factor receptor (EGFR) is a type-1 transmembrane receptor tyrosine kinase, which activates the downstream signaling cascades in many tumors, such as oral and lung cancers. We previously developed EMab-134, a novel anti-EGFR monoclonal antibody (mAb), which reacts with endogenous...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Kaneko, Mika K., Yamada, Shinji, Itai, Shunsuke, Chang, Yao-Wen, Nakamura, Takuro, Yanaka, Miyuki, Kato, Yukinari
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986659/
https://ncbi.nlm.nih.gov/pubmed/29872734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.03.010
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