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Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins
Destruxins, secondary metabolites of entomopathogenic fungi, exert a wide variety of interesting characteristics ranging from antiviral to anticancer effects. Although their mode of action was evaluated previously, the molecular mechanisms of resistance development are unknown. Hence, we have establ...
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| Vydáno v: | Oncotarget |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986646/ https://ncbi.nlm.nih.gov/pubmed/29876015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25432 |
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