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Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins
Destruxins, secondary metabolites of entomopathogenic fungi, exert a wide variety of interesting characteristics ranging from antiviral to anticancer effects. Although their mode of action was evaluated previously, the molecular mechanisms of resistance development are unknown. Hence, we have establ...
Shranjeno v:
| izdano v: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986646/ https://ncbi.nlm.nih.gov/pubmed/29876015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25432 |
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