Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells

Hypoxia, a hallmark characteristic of glioblastoma (GBM) induces changes in the transcriptome and the proteome of tumor cells. We discovered that hypoxic stress produces significant qualitative and quantitative changes in the protein content of secreted exosomes from GBM cells. Among the proteins fo...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Kore, Rajshekhar A., Edmondson, Jacob L., Jenkins, Samir V., Jamshidi-Parsian, Azemat, Dings, Ruud P.M., Reyna, Nathan S., Griffin, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986551/
https://ncbi.nlm.nih.gov/pubmed/29872742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.03.008
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