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Expansion of transplanted islets in mice by co-transplantation with adipose tissue-derived mesenchymal stem cells

The shortage of donor islets is a significant obstacle for widespread clinical application of pancreatic islet transplantation. To investigate whether adipose tissue-derived mesenchymal stem cells (ADSCs) induce expansion of transplanted islets, we performed co-transplantation experiments in a mouse...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Tanaka, Tomoko, Kojima, Daibo, Mera, Toshiyuki, Matsumoto, Masahito, Yasunami, Yohichi, Yanase, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986537/
https://ncbi.nlm.nih.gov/pubmed/29872765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e00632
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