In Vivo Phosphoproteome Analysis Reveals Kinome Reprogramming in Hepatocellular Carcinoma

Aberrant kinases contribute to cancer survival and proliferation. Here, we quantitatively characterized phosphoproteomic changes in an HBx-transgenic mouse model of hepatocellular carcinoma (HCC) using high-resolution mass spectrometry, profiled 22,539 phosphorylation sites on 5431 proteins. Using a...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Proteomics
Hoofdauteurs: Ren, Liangliang, Li, Chaoying, Wang, Youliang, Teng, Yan, Sun, Huichuan, Xing, Baocai, Yang, Xiao, Jiang, Ying, He, Fuchu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986249/
https://ncbi.nlm.nih.gov/pubmed/29472430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000421
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