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Grasping the nettle: A bacterial invasin that targets immunoglobulin variable domains
In a new paper, the protein InvD from Yersinia pseudotuberculosis, a zoonotic pathogen, is shown to assist late-stage invasion of intestinal epithelia. Remarkably, InvD acts by binding the Fab region of IgG or IgA. It straddles adjacent light-chain and heavy-chain variable domains, but its binding i...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986225/ https://ncbi.nlm.nih.gov/pubmed/29858390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.002949 |
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