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Tankyrase modulates insulin sensitivity in skeletal muscle cells by regulating the stability of GLUT4 vesicle proteins

Tankyrase 1 and 2, members of the poly(ADP-ribose) polymerase family, have previously been shown to play a role in insulin-mediated glucose uptake in adipocytes. However, their precise mechanism of action, and their role in insulin action in other cell types, such as myocytes, remains elusive. Treat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Su, Zhiduan, Deshpande, Vinita, James, David E., Stöckli, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986224/
https://ncbi.nlm.nih.gov/pubmed/29669812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001058
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