Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility

RATIONALE: The promising clinical benefits of delivering human mesenchymal stem cells (hMSCs) for treating heart disease warrant a better understanding of underlying mechanisms of action. hMSC exosomes increase myocardial contractility; however, the exosomal cargo responsible for these effects remai...

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Publicado en:Circ Res
Main Authors: Mayourian, Joshua, Ceholski, Delaine K., Gorski, Przemek A., Mathiyalagan, Prabhu, Murphy, Jack F., Salazar, Sophia I., Stillitano, Francesca, Hare, Joshua M., Sahoo, Susmita, Hajjar, Roger J., Costa, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986183/
https://ncbi.nlm.nih.gov/pubmed/29449318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.312420
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