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Insight into the substrate specificity change caused by the Y227H mutation of α-glucosidase III from the European honeybee (Apis mellifera) through molecular dynamics simulations

Honey from the European honeybee, Apis mellifera, is produced by α-glucosidases (HBGases) and is widely used in food, pharmaceutical, and cosmetic industries. Categorized by their substrate specificities, HBGases have three isoforms: HBGase I, II and III. Previous experimental investigations showed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Na Ayutthaya, Pratchaya Pramoj, Chanchao, Chanpen, Chunsrivirot, Surasak
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986129/
https://ncbi.nlm.nih.gov/pubmed/29864156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198484
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