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Hapalindole H Induces Apoptosis as an Inhibitor of NF-κB and Affects the Intrinsic Mitochondrial Pathway in PC-3 Androgen-insensitive Prostate Cancer Cells

BACKGROUND: Prostate cancer presents the highest incidence rates among all cancer in men. Hapalindole H (Hap H), isolated from Fischerella muscicola (UTEX strain number LB1829) as part of our natural product anticancer drug discovery program, was found to be significantly active against prostate can...

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Bibliografische gegevens
Gepubliceerd in:Anticancer Res
Hoofdauteurs: Acuña, Ulyana Muñoz, Mo, Shunyan, Zi, Jiachen, Orjala, Jimmy, Carcache de Blanco, Esperanza J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986100/
https://ncbi.nlm.nih.gov/pubmed/29848677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/anticanres.12595
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