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5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

BACKGROUND: Nowadays, cancer is an important public health problem in all countries. Limitations of current chemotherapy for neoplastic diseases such as severe adverse reactions and tumor resistance to the chemotherapeutic drugs have been led to a temptation for focusing on the discovery and develop...

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Publicat a:Drug Des Devel Ther
Autors principals: Gomha, Sobhi M, Edrees, Mastoura M, Muhammad, Zeinab A, El-Reedy, Ahmed AM
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985782/
https://ncbi.nlm.nih.gov/pubmed/29881258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S165276
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