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5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

BACKGROUND: Nowadays, cancer is an important public health problem in all countries. Limitations of current chemotherapy for neoplastic diseases such as severe adverse reactions and tumor resistance to the chemotherapeutic drugs have been led to a temptation for focusing on the discovery and develop...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Gomha, Sobhi M, Edrees, Mastoura M, Muhammad, Zeinab A, El-Reedy, Ahmed AM
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985782/
https://ncbi.nlm.nih.gov/pubmed/29881258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S165276
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