Splicing Factor 3B1 hypomethylation is associated with altered SF3B1 transcript expression in older humans

Ageing in man is associated with changes to the splicing factor pool. A proportion of splicing factors are regulated during ageing by mechanisms involving the Ataxia Telangiectasia Mutated (ATM) gene, but the factors that determine the remaining proportion have yet to be identified. DNA methylation...

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Bibliografiska uppgifter
I publikationen:Mech Ageing Dev
Huvudupphovsmän: Holly, Alice C., Pilling, Luke C., Hernandez, Dena, Lee, Benjamin P., Singleton, Andrew, Ferrucci, Luigi, Melzer, David, Harries, Lorna W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985527/
https://ncbi.nlm.nih.gov/pubmed/24463145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.01.005
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