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pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics

Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important disease states including cardiovascular disease an...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Caprio, Vittorio, Badimon, Lina, Di Napoli, Mario, Fang, Wen-Hui, Ferris, Glenn R., Guo, Baoqiang, Iemma, Rocco S., Liu, Donghui, Zeinolabediny, Yasmin, Slevin, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985513/
https://ncbi.nlm.nih.gov/pubmed/29892284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01089
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