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K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions

Ras is a membrane-anchored signaling protein that serves as a hub for many signaling pathways and also plays a prominent role in cancer. The intrinsic behavior of Ras on the membrane has captivated the biophysics community in recent years, especially the possibility that it may form dimers. In this...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Chung, Jean K., Lee, Young Kwang, Denson, John-Paul, Gillette, William K., Alvarez, Steven, Stephen, Andrew G., Groves, Jay T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984903/
https://ncbi.nlm.nih.gov/pubmed/29320680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.042
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