Recurrent rearrangements of FOS and FOSB define osteoblastoma

The transcription factor FOS has long been implicated in the pathogenesis of bone tumours, following the discovery that the viral homologue, v-fos, caused osteosarcoma in laboratory mice. However, mutations of FOS have not been found in human bone-forming tumours. Here, we report recurrent rearrange...

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Publicado no:Nat Commun
Main Authors: Fittall, Matthew W., Mifsud, William, Pillay, Nischalan, Ye, Hongtao, Strobl, Anna-Christina, Verfaillie, Annelien, Demeulemeester, Jonas, Zhang, Lei, Berisha, Fitim, Tarabichi, Maxime, Young, Matthew D., Miranda, Elena, Tarpey, Patrick S., Tirabosco, Roberto, Amary, Fernanda, Grigoriadis, Agamemnon E., Stratton, Michael R., Van Loo, Peter, Antonescu, Cristina R., Campbell, Peter J., Flanagan, Adrienne M., Behjati, Sam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984627/
https://ncbi.nlm.nih.gov/pubmed/29858576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04530-z
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