Dynamic structural states of ClpB involved in its disaggregation function

The ATP-dependent bacterial protein disaggregation machine, ClpB belonging to the AAA+ superfamily, refolds toxic protein aggregates into the native state in cooperation with the cognate Hsp70 partner. The ring-shaped hexamers of ClpB unfold and thread its protein substrate through the central pore....

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Bibliographic Details
Published in:Nat Commun
Main Authors: Uchihashi, Takayuki, Watanabe, Yo-hei, Nakazaki, Yosuke, Yamasaki, Takashi, Watanabe, Hiroki, Maruno, Takahiro, Ishii, Kentaro, Uchiyama, Susumu, Song, Chihong, Murata, Kazuyoshi, Iino, Ryota, Ando, Toshio
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984625/
https://ncbi.nlm.nih.gov/pubmed/29858573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04587-w
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