Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma

Circulating tumor-derived DNA testing for cancer screening has recently been demonstrated in a prospective study on identification of nasopharyngeal carcinoma (NPC) among 20,174 asymptomatic individuals. Plasma EBV DNA, a marker for NPC, was detected using real-time PCR. While plasma EBV DNA was per...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lam, W. K. Jacky, Jiang, Peiyong, Chan, K. C. Allen, Cheng, Suk H., Zhang, Haiqiang, Peng, Wenlei, Tse, O. Y. Olivia, Tong, Yu K., Gai, Wanxia, Zee, Benny C. Y., Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C., Woo, John K. S., Chiu, Rossa W. K., Lo, Y. M. Dennis
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984543/
https://ncbi.nlm.nih.gov/pubmed/29760067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804184115
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