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Genetic instrumental variable regression: Explaining socioeconomic and health outcomes in nonexperimental data

Identifying causal effects in nonexperimental data is an enduring challenge. One proposed solution that recently gained popularity is the idea to use genes as instrumental variables [i.e., Mendelian randomization (MR)]. However, this approach is problematic because many variables of interest are gen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: DiPrete, Thomas A., Burik, Casper A. P., Koellinger, Philipp D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984483/
https://ncbi.nlm.nih.gov/pubmed/29686100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707388115
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