Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats

BACKGROUND: A low-protein diet supplemented with ketoacids (LPD + KA) maintains the nutritional status of patients with chronic kidney disease (CKD). Oxidative damage and mitochondrial dysfunction associated with the upregulation of p66SHC and FoxO3a have been shown to contribute to muscle atrophy....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Skelet Muscle
Egile Nagusiak: Wang, Dongtao, Wei, Lianbo, Yang, Yajun, Liu, Huan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984473/
https://ncbi.nlm.nih.gov/pubmed/29855350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-018-0164-z
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