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Epigenetic regulators: multifunctional proteins modulating hypoxia-inducible factor-α protein stability and activity
The hypoxia-inducible factor (HIF) is a heterodimeric transcription factor governing a transcriptional program in response to reduced O(2) availability in metazoans. It contributes to physiology and pathogenesis of many human diseases through its downstream target genes. Emerging studies have shown...
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| Published in: | Cell Mol Life Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer International Publishing
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984203/ https://ncbi.nlm.nih.gov/pubmed/29032501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2684-9 |
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