SINGLE-CELL CHROMATIN MODIFICATION PROFILING REVEALS INCREASED EPIGENETIC VARIATIONS WITH AGING

Post-translational modifications of histone proteins and exchanges of histone variants at chromatin are central to the regulation of nearly all DNA-templated biological processes. However, the degree and variability of chromatin modifications in specific human immune cells remain largely unknown. He...

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Publicado en:Cell
Main Authors: Cheung, Peggie, Vallania, Francesco, Warsinske, Hayley C., Donato, Michele, Schaffert, Steven, Chang, Sarah E., Dvorak, Mai, Dekker, Cornelia L., Davis, Mark M., Utz, Paul J., Khatri, Purvesh, Kuo, Alex J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984186/
https://ncbi.nlm.nih.gov/pubmed/29706550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.079
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