Llwytho...

Artificial Anti-tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types

We have engineered a panel of novel Fn3 scaffold-based proteins that bind with high specificity and affinity to each of the individual mouse Fcγ receptors (mFcγR). These binders were expressed as fusions to anti-tumor antigen single chain antibodies and mouse serum albumin, creating opsonizing agent...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Biol
Prif Awduron: Chen, Tiffany F., Li, Kevin K., Zhu, Eric F., Opel, Cary F., Kauke, Monique J., Kim, Heeyoon, Atolia, Eta, Wittrup, K. Dane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984174/
https://ncbi.nlm.nih.gov/pubmed/29704491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.04.021
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!