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Artificial Anti-tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types
We have engineered a panel of novel Fn3 scaffold-based proteins that bind with high specificity and affinity to each of the individual mouse Fcγ receptors (mFcγR). These binders were expressed as fusions to anti-tumor antigen single chain antibodies and mouse serum albumin, creating opsonizing agent...
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| Gepubliceerd in: | J Mol Biol |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984174/ https://ncbi.nlm.nih.gov/pubmed/29704491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.04.021 |
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