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Shifting the IGF-axis: an age-related decline in human tear IGF-1 correlates with clinical signs of dry eye

OBJECTIVE: The human corneal epithelium expresses both the insulin-like growth factor type 1 receptor (IGF-1R) and the IGF-1R/insulin receptor (INSR) hybrid. Despite the previous identification of IGF-1 in human tear fluid, little is known regarding the regulation of IGF-1 in tear fluid and its role...

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Detalhes bibliográficos
Publicado no:Growth Horm IGF Res
Main Authors: Patel, Roshni, Zhu, Meifang, Robertson, Danielle M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984117/
https://ncbi.nlm.nih.gov/pubmed/29452886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2018.02.001
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