Liraglutide reduces hepatic glucolipotoxicity-induced liver cell apoptosis through NRF2 signaling in Zucker diabetic fatty rats

The primary aim of the present study was to evaluate the effects of liraglutide on glucolipotoxicity-induced liver cell apoptosis and the underlying mechanisms in Zucker diabetic fatty (ZDF) rats. The results revealed that liraglutide significantly decreased the body weight, hyperglycemia and hyperl...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Guo, Jun, Li, Cai, Yang, Chunxiao, Li, Bing, Wei, Jie, Lin, Yajun, Ye, Peng, Hu, Gang, Li, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984007/
https://ncbi.nlm.nih.gov/pubmed/29693190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8919
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