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IL-6 signaling by STAT3 participates in the change from hyperplasia to neoplasia in NRP-152 and NRP-154 rat prostatic epithelial cells

BACKGROUND: STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6 signaling and phosphorylation of STAT3 in 2 rat prostatic epithelial lines. NRP-152 and NRP-154 cells were derived from the same rat prostate...

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Détails bibliographiques
Auteurs principaux: Barton, Beverly E, Murphy, Thomas F, Adem, Patricia, Watson, Richard A, Irwin, Robert J, Huang, Hosea F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC59840/
https://ncbi.nlm.nih.gov/pubmed/11710966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-1-19
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