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Loss of RUNX3 is significantly associated with advanced tumor grade and stage in endometrial cancers

Loss of runt-related transcription factor 3 (RUNX3) has been reported in various cancers, and one of the mechanisms mediating loss of RUNX3 expression is DNA methylation. However, the role of RUNX3 expression and its DNA methylation status as prognostic factors in endometrial cancer remain unclear....

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Jeong, Dongjun, Kim, Hyungjoo, Ryu, Aeli, Sunwoo, Jaegun, Choi, Seung Do, Nam, Gye Hyun, Jeon, Seob
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983989/
https://ncbi.nlm.nih.gov/pubmed/29693143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8915
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