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The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

Bornyl cis-4-hydroxycinnamate, an active compound isolated from Piper betle stems, was investigated in terms of its effects on A2058 and A375 melanoma cell proliferation and protein expression in this study. We used flow cytometric analysis to examine the early stages of apoptosis induced by bornyl...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Yang, Tzu-Yen, Wu, Yu-Jen, Chang, Chi-I, Chiu, Chien-Chih, Wu, Mei-Li
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983650/
https://ncbi.nlm.nih.gov/pubmed/29734677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051370
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