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Synthesis, Molecular Structure, Anticancer Activity, and QSAR Study of N-(aryl/heteroaryl)-4-(1H-pyrrol-1-yl)Benzenesulfonamide Derivatives

A series of N-(aryl/heteroaryl)-4-(1H-pyrrol-1-yl)benzenesulfonamides were synthesized from 4-amino-N-(aryl/heteroaryl)benzenesulfonamides and 2,5-dimethoxytetrahydrofuran. All the synthesized compounds were evaluated for their anticancer activity on HeLa, HCT-116, and MCF-7 human tumor cell lines....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Żołnowska, Beata, Sławiński, Jarosław, Brzozowski, Zdzisław, Kawiak, Anna, Belka, Mariusz, Zielińska, Joanna, Bączek, Tomasz, Chojnacki, Jarosław
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983619/
https://ncbi.nlm.nih.gov/pubmed/29772699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051482
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