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TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

Transforming growth factor-β (TGF-β) is a cytokine essential for the induction of the fibrotic response and for the activation of the cancer stroma. Strong evidence suggests that a strong cross-talk exists among TGF-β and the tissue extracellular matrix components. TGF-β is stored in the matrix as p...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Caja, Laia, Dituri, Francesco, Mancarella, Serena, Caballero-Diaz, Daniel, Moustakas, Aristidis, Giannelli, Gianluigi, Fabregat, Isabel
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983604/
https://ncbi.nlm.nih.gov/pubmed/29701666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051294
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